Example: PlayMancer

PlayMancer is a platform for rapid development of serious games, with a special focus on therapeutic support games for behavioral and addictive disorders. It is modular and combines techniques from multimodal interaction (speech, touch, biosensors and motion-tracking), 3D engines, virtual and augmented reality, speech recognition and natural language processing.

http://youtu.be/8AS4p_YYxMk
http://youtu.be/SPSFDvVYa_s

Paper: Motivation based difficulty adaptation for therapeutic games

Hocine, N.; Gouaich, A.; Di Loreto, I.; Joab, M., "Motivation based difficulty adaptation for therapeutic games," Serious Games and Applications for Health (SeGAH), 2011 IEEE 1st International Conference on , vol., no., pp.1,8, 16-18 Nov. 2011

This paper presents presents a difficulty adaptation technique dedicated to a family of therapeutic games for post-stroke rehabilitation based on therapeutic serious game, they focus in upper limb rehabilitation.

As introduction they talk about studies that suggest intensive training (many repetitions) while giving feedbacks and motivating the patients can have an important impact on the patients’ skills recover.  And a person who enjoys what he is doing spends more time developing his skills in a given activity.

They developed a game that is based on the Wii-balance from Nintendo. This game aims to improve player’s equilibrium capabilities while achieving the game goals.