Example: PlayMancer

PlayMancer is a platform for rapid development of serious games, with a special focus on therapeutic support games for behavioral and addictive disorders. It is modular and combines techniques from multimodal interaction (speech, touch, biosensors and motion-tracking), 3D engines, virtual and augmented reality, speech recognition and natural language processing.

http://youtu.be/8AS4p_YYxMk
http://youtu.be/SPSFDvVYa_s